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Major outcomes from MADIT II trial
2019-05-22
Major outcomes from MADIT-II trial suggested that, once again, the risk of death in defibrillator group was significantly less than conventional-therapy group with hazard ratio of 0.69. In this trial, the major drawback was corrected. The medication use remained balanced between ICD patients, and co
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br Epidemiology Electrophysiological BrS phenotypes occur pr
2019-05-22
Epidemiology Electrophysiological BrS phenotypes occur predominantly in young male adults (by adenosine receptor agonist rate, autonomic nervous system activity, some types of drugs, and a febrile state. Therefore, the true prevalence of BrS in the general population is difficult to estimate. Ho
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br OPG RANK and RANKL contribute to the vicious cycle
2019-05-22
OPG, RANK and RANKL contribute to the vicious cycle established between tumour conotoxin and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several argum
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br The study by Jesse
2019-05-21
The study by Jesse Berman and colleagues published in is the first to systematically analyse the risk of hospital admissions and mortality associated with drought periods in the USA. As the authors state, this is an understudied topic, but of great concern in the USA and globally as climate chang
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El proceso hist rico de conformaci n del Estado en
2019-05-21
El proceso histórico de conformación del Estado en Chile, su momento constitutivo en el siglo xix es precisamente la invasión del Estado liberal chileno a territorio de los pueblos originarios; desposesión que disocia la comunidad cultural mapuche de la soberanía territorial que hasta ese momento ha
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El n mero de correspondiente al segundo semestre
2019-05-21
El número 61 de , correspondiente al segundo semestre de 2015, ofrece seis artículos en su sección Política y Sociedad. El primero HZ-1157 cargo de Wilfredo Padrón Iglesias, “La masonería, un punto sombrío en la trayectoria de Francisco de Miranda”, trata sobre esta importante figura, quien es consi
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Upon diagnosis the patient s lymphoma and HLH represented a
2019-05-21
Upon diagnosis, the patient׳s lymphoma and HLH represented a therapeutic dilemma. Effective early therapy reduces mortality of HLH from 95% to 30–35% [4]. The HLH-2004 treatment protocol consists of T-cell targeted immunosupression with dexamethasone and cyclosporine, macrophage targeted etoposide w
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br Commentary Her ECG showed a regular wide QRS complex
2019-05-21
Commentary Her ECG showed a regular wide QRS complex tachycardia at a rate of 130 beats per minute. The morphology of the QRS complex exhibited the right BBB (RBBB) pattern with inferior axis. The duration of the QRS complex was 0.16s. P waves of sinus origin were not seen, presumably hidden in t
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The lead ECG and dimensional geometrical maps for
2019-05-21
The 12-lead ECG and 2-dimensional geometrical maps for corrected RT interval difference and corrected Tp–e interval difference obtained by using 187-ch RIDM-ECG before and during the intravenous amiodarone infusion for representative cases are shown in Figs. 1 and 2 respectively. The mean value of Q
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Phosphorus is essential for organic activity such as cellula
2019-05-21
Phosphorus is essential for organic activity such as cellular signal transduction, membrane transport, mineral metabolism, and order Zalcitabine exchange [1]. Bone and teeth store 80% of the total body phosphorus. Intracellular phosphorus consists of the form of organic compounds such as adenosine t
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Eastern European countries have undergone many socioeconomic
2019-05-21
Eastern European countries have undergone many socioeconomic changes in the past two decades. In particular, in Russia, alcohol was strongly associated with adult mortality. More than half of deaths in Russian men are attributable to cardiovascular disease, with hypertension, hypercholesterolaemia,
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Of note gender equity might
2019-05-21
Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low
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br Authors disclosure Mark Clemons received honoraria for ta
2019-05-20
Authors\' disclosure Mark Clemons received honoraria for talks from Novartis and Amgen, research funding from Novartis. Case In September 2007 a 9½-year-old boy was diagnosed with a Ewing sarcoma (EWS-FL1 translocation positive) of the right scapula. MRI showed a tumor of 8.0×2.9 ×6.2cm locat
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Well designed operational research is
2019-05-20
Well designed operational research is needed to refine this starting point. Research is also needed to find out whether prophylactic valganciclovir treatment in high-risk patients might reduce AIDS mortality as well as blindness, as substantial data suggest. WHO leadership is needed to provide cytom
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Social determinants are the lived conditions
2019-05-20
Social determinants are the lived conditions (ie, social and economic) that influence wellbeing, and environmental influences on behaviour are those assessed with the health behaviour theory. Stages of change models (ie, those that recognise health behaviour as a series of progressive steps leading
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