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S63845 The p MAPK pathway activates AP to regulate
2019-04-22
The p38 MAPK pathway activates AP1 to regulate transcription of TNF-α [32,33]. Our results show that EC inhibits the expression of total c-Jun and p-c-Jun in the lungs of LPS-challenged mice. This finding suggests that EC may inhibit TNF-α production in the lungs via the p38 MAPK–AP1 signaling pathw
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In addition the TAA treated groups show http
2019-04-22
In addition, the TAA-treated groups showed a significant reduction in body weight with significantly increased liver weights and sizes compared to control rats, but NJ cotreatment reversed those defects (Table 1). The reduction in body weights could be attributed to the toxic effect of TAA throughou
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br Radiofrequency ablation Application of single radiofreque
2019-04-22
Radiofrequency ablation Application of single radiofrequency insulin receptor inhibitor to the earliest atrial activation site during tachycardia terminated the tachycardia and restored sinus rhythm (Fig. 4). Because the local AF in the SVC continued, we confirmed that isolation of the SVC from
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br What is the best
2019-04-22
What is the best pacing algorithm for vasovagal syncope? Conclusions Conflict of interest Introduction The number of implantations of cardiovascular implantable electronic devices (CIEDs), including permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs), and cardiac
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Pain flare defined as a temporary
2019-04-22
Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte
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br Material and methods br Results
2019-04-22
Material and methods Results Thirty-one patients were enrolled consecutively, in this randomized study, between January 2010 and March 2012. The mean age was 65.5±13.7 years. The proportion of patients with primary prevention indication was 25.8% and ischemic cardiomyopathy was 29.0%. All repo
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br Results br Discussion We identified
2019-04-22
Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat
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Eastern European countries have undergone
2019-04-22
Eastern European countries have undergone many socioeconomic changes in the past two decades. In particular, in Russia, alcohol was strongly associated with adult mortality. More than half of deaths in Russian men are attributable to cardiovascular disease, with hypertension, hypercholesterolaemia,
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Vaccinated individuals might represent a
2019-04-22
Vaccinated individuals might represent a safer source of hyperimmune serum. Two vaccine candidates will be tested soon in west Africa. If serum from vaccinated individuals has neutralising activity against the virus in cell models, this serum could be used as adjuvant therapy for EVD. In parallel, a
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Buturovic and Ignatovic rightly point out that
2019-04-22
Buturovic and Ignatovic rightly point out that present-day formula is different from the type of milk received by Brazilian infants born in the early 1980s, particularly because long-chain polyunsaturated fatty acids have been added to modern products. Nevertheless, modern biology is constantly unco
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Esta postura foi decisiva para as alian as confeccionadas
2019-04-22
Esta postura foi decisiva para as alianças confeccionadas pelas lideranças políticas e/ou religiosas (neo) pentecostais nas eleições seguintes. O apoio a Collor em 1989 e a Fernando Henrique Cardoso em 1994 teve como objetivo a oposição ao candidato Lula, do Partido dos Trabalhadores (pt), à Presidê
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M s all del justificado resentimiento de los
2019-04-20
Más allá del justificado resentimiento de los tamaulipecos, es el escritor Mauricio Magdaleno en su antología Escritores extranjeros en la Revolución (1979), quien ofrece el juicio más interesante sobre la novela, en su breve presentación del autor norteamericano. A diferencia de Gunn, para quien Ta
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Sor Juana cuyo genio era para Vigil indudablemente antimonac
2019-04-20
Sor Juana, cuyo genio era para Vigil indudablemente “antimonacal” —recordemos que estamos en pleno periodo posterior Sunitinib las leyes de desamortización de los bienes eclesiásticos— tuvo que tomar una decisión “dictada por las exigencias de su sociedad”, por ello, continúa Vigil, si hubiese naci
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Si los sicarios y sus c rteles ejercen un
2019-04-20
Si los sicarios y sus cárteles ejercen un oficio de tinieblas, donde “madrugar” es uno de los ejes rectores de un México violento, zafio, “kafkiano” y pulsante de impunidad, para Juan Villoro: Circunscrito por el crimen, la miseria y la muerte, el tema de una juventud cercada por la violencia es t
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Brasil y Argentina son los
2019-04-20
Brasil y Argentina son los dos países que comparten fronteras con todos los países restantes del bloque primigenio. Aun así, sus legislaciones abordan el tema en menor profundidad en comparación ketotifen fumarate como lo hacen Paraguay y Uruguay. En Brasil, la Ley 11445 es la que refleja en cierta
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