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Our analysis has devoted limited
2023-04-14

Our analysis has devoted limited attention to the standard corporate tax scheme with deductibility for interest payments that is in place in most countries. A conventional corporate tax scheme offers partial deduction of capital costs, and can be interpreted as a change in the degree of capital cost
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Composite soil samples were transported to the laboratory an
2023-04-14

Composite soil samples were transported to the laboratory and then dried, crushed and passed through a 2mm sieve was. Sample digestion and release of elements method Sposito was performed [15]. Accordingly, taking into account soil moisture to 2g soil samples 12.5ml of nitric acid was added 4M. Samp
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br Acknowledgments This work was supported by
2023-04-14

Acknowledgments This work was supported by the Swiss National Science Foundation. 15-Lipoxygenase 1 (15-LOX-1) is a nonheme, iron-containing enzyme predominantly expressed in reticulocytes, eosinophils, macrophages, mast cells, and bronchial epithelial cells . 15-LOX-1 is a key enzyme involved
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Previous studies have demonstrated ATR inhibition is effecti
2023-04-14

Previous studies have demonstrated ATR inhibition is effective for treating cancers combining with chemotherapies in lung adenocarcinoma, gastric cancer, HER2 positive breast cancer and chronic lymphocytic leukemia nuciferine to enhance chemotherapy sensitivity [[16], [17], [18],[20], [21], [22]].
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Despite their different effects on cell survival the functio
2023-04-14

Despite their different effects on cell survival, the functions of autophagy and apoptosis are not completely independent. Additionally, Cho et al. (2009) suggested that the mediation of caspase-3 links the apoptotic and autophagic signaling pathways. Consequently, to illuminate the correlation, exc
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The reduction of heterodimerization of KOR and APJ by
2023-04-14

The reduction of heterodimerization of KOR and APJ by both doses of apelin found in the present study may result in inducing protective effects of apelin on the myocardium imposed to high pressure in renovascular hypertension conditions. The finding that apelin in both doses reduced heterodimerizati
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BAY 11-7082 This suggestion was confirmed by immunohistochem
2023-04-13

This suggestion was confirmed by immunohistochemical studies in which the immunoreactivity of the enzyme was actually higher at the earlier rather than at the advanced stages of the disease. Importantly, a later study showed that the biochemical signature of 12/15LO enzymatic activation (i.e., 12-HE
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The relationship between AG and tau deposition in the presen
2023-04-13

The relationship between AG and tau deposition in the presence of Aβ burden warrants more research in AD and in other primary tauopathies (not associated with accumulation of Aβ plaques). Our findings highlight the importance of measuring AG, as this relationship was not evident for total GS-9350 sa
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Oleandrin receptor It has been largely demonstrated that sev
2023-04-12

It has been largely demonstrated that several clinico-pathological factors influence ovarian cancer patients' prognosis, including residual tumor at primary cytoreductive surgery, FIGO stage, tumor grading, cancer histology and performance status [3,4]. Nevertheless, the recent awareness achieved in
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Activation of AhR is also known to
2023-04-12

Activation of AhR is also known to upregulate the expression of AhRR (AhR repressor), an inhibitor protein of AhR [29]. However, the exact mechanism by which AhRR represses AhR signaling is not well understood. The initial study by Mimura and colleagues suggested that AhRR is capable of directly com
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Polycyclic aromatic hydrocarbons PAHs are
2023-04-12

Polycyclic aromatic hydrocarbons (PAHs) are abundant environmental contaminants that are produced by the incomplete combustion of organic matter, combustion engines, residential heating, 1145 burning, and industrial activities (Gelboin, 1980; Phillips, 1999, Phillips, 2002). Some PAHs have been reco
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Involvement of Adiponectin in the regulation of
2023-04-12

Involvement of Adiponectin in the regulation of imatinib resistance in human CML cells has not been hitherto examined. Therefore, in this study, we first established imatinib-resistant K562 CML cells, and then evaluated the effect of Adiponectin in reversing imatinib resistance. The data presented h
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br Material and methods br Results br Discussion T
2023-04-12

Material and methods Results Discussion T2D is a substantial threat to global human health [31]. Obesity-associated chronic low-grade inflammation promotes insulin resistance and T2D [32]. In obese individuals, the production of numerous inflammatory molecules including IL-6 and TNF-a is up
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Chlorogenic acid an abundant polyphenol found
2023-04-12

Chlorogenic alkylation of dna (7), an abundant polyphenol found in coffee and the human diet, has various biological activities including antioxidant and anticancer effects [54]. Jiang et al. reported that compound 7 had a selective cytotoxic activity on human oral tumor cells (HSG, HSC-2) as compar
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br Conclusion br References and
2023-04-12

Conclusion References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Acknowledgements Introduction Nucleosome, the basic chromatin unit, is composed of DNA and core histones (H2A, H2B, H3 and H4) and organized into
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