• The compounds listed in Table Table Table Table

  2020-01-10

  

  The compounds listed in Table 1, Table 2, Table 3, Table 4, Table 5 were biologically evaluated for their inhibition of the specific binding of a radiolabeled ligand [3H]PGE2 to membrane fractions prepared from cells stably expressing each mouse prostanoid receptor. The EP1 antagonist activity of th

• In mammals neutrophil elastase is a trypsin like

  2020-01-10

  

  In mammals, neutrophil elastase is a trypsin-like serine protease stored in the azurophilic granules of naïve neutrophils [15], [16]. The catalytic activity of neutrophil elastase relies on a His57–Asp102–Ser195 triad (chymotrypsin numbering system) that functions by transfer of electrons from the c

• While these previous correlative studies have measured tDDR

  2020-01-10

  

  While these previous correlative studies have measured tDDR1 protein by IHC, these studies have not considered that pDDR1 could also be an important marker of cancer prognosis. A phosphoproteomic survey of lung cancer tissues did identify pDDR1 as one of the most commonly phosphorylated receptor kin

• The cholinergic system has been

  2020-01-09

  

  The cholinergic system has been shown to play a role in regulation of the inflammatory response [13] as well as in the influence of the metabolism of PCa cells [14]. The reduced activity of cholinesterase (ChoE) and the consequent increased amount of biperiden has been shown to lead to a cholinergi

• Furthermore certain components in the Melanocyte Growth Medi

  2020-01-09

  

  Furthermore, certain components in the Melanocyte Growth Medium seem to influence the response to UV radiation [17]: UV-induced effects on tyrosinase activity were less distinct in melanocytes cultured with phorbol 12-myristate 13-acetate [18], which was also an ingredient in our Melanocyte Growth M

• Phenolic compounds generated during biomass pretreatment inh

  2020-01-09

  

  Phenolic compounds generated during W-7 hydrochloride pretreatment inhibit and/or deactivate cellulolytic/hemicellulolytic enzymes as well as the viability and fermentative capacity of yeast and bacteria [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]. Phenolic compounds cause changes in prote

• For these reasons molecules of the ET family and in

  2020-01-09

  

  For these reasons, molecules of the ET family and in particular ET-1 are considered useful factors in the evaluation of malignancy and in consequence, in the prognosis for several forms of neoplasia, such as ovarian (Bagnato et al., 2005), prostate (Nelson et al, 1995, Nelson et al, 1996), colorecta

• CYP A is involved in the enzymatic oxidation

  2020-01-09

  

  CYP3A is involved in the enzymatic A-71623 of many therapeutic agents [29]. The activity of BFCOD has been used to monitor CYP3A activity in humans [30], pigs [31], mice [32], and fish [23]. The predominant isoform expressed in the human liver is CYP3A4 [33]. In pigs, CYP3A29 contributes most to CY

• Due to its several industrial applications the recombinant p

  2020-01-09

  

  Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian c-met inhibitor (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms (Tomita et al.,

• The oxidation of the lipid fraction of

  2020-01-09

  

  The oxidation of the lipid fraction of meat is an extremely complex process because of the high sensitivity of oxidation products to decomposition, their reactions with other components, the complex effect of catalysts and the presence of antioxidants. These changes are the main cause of limited she

• To understand more clearly how these activities are combined

  2020-01-09

  

  To understand more clearly how these activities are combined in the heterotrimeric enzyme and to understand more clearly how DNA alkylation might effect DNA helicase activity, we summarize the relevant features of the structure of RecBCD determined in the presence of DNA. The RecB and RecC subunits

• Renal injury by cisplatin has been associated

  2020-01-09

  

  Renal injury by cisplatin has been associated with oxidative stress, inflammation, and apoptosis (Francescato et al., 2007, Iseri et al., 2007, Kiymaz et al., 2008, Ueki et al., 2012). Specifically, apoptosis is an important mode of cell death in cisplatin nephrotoxicity, and many studies including

• br Introduction Fibroblast growth factors FGF are a

  2020-01-09

  

  Introduction Fibroblast growth factors (FGF) are a family of 18 secreted ligands that bind to four receptor tyrosine kinase (RTK) FGF receptors (FGFR1–4). The interaction of FGFs with their cognate receptors results in the activation of a number of downstream signaling pathways, including the MAP

• It has been reported that

  2020-01-09

  

  It has been reported that Eph/Ephrin are involved in the regulation of the tumor angiogenesis [10], [11], [12]. The distinct and specific involvement of AZD-9291 and veins in tumor angiogenesis is unclear. EphrinB2 is expressed in arteries and its receptor EphB4 is expressed in veins; these molecul

• The applications of fungal enzymes

  2020-01-09

  

  The applications of fungal enzymes in paper industry involve biobleaching of pulp, pulp de-inking, degradation of dissolved and suspended organic compounds in concentrated effluents of mills and enhanced fibrillation. Enzymes usage is encouraged in paper industry in order to reduce the use of chemic

15399 records 880/1027 page Previous Next First page 上5页 876877878879880 下5页 Last page