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These cognitive deficits may suggest that cognitive therapy
2019-08-16
These cognitive deficits may suggest that cognitive therapy and pharmacotherapy for gambling behavior may ultimately wish to consider genotyping as a means of better targeting treatment approaches. If core cognitive deficits are shown consistently in certain subgroups of gamblers based on genotype,
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The present work shows that
2019-08-15
The present work shows that normal climatic conditions are not critical for the long time survival of DNA in untreated blood stains. This information may be useful for laboratories who wish to store reference blood samples in a simple way, while saving the costs of commercial substrates that are tre
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DNMT is the dominating enzyme responsible
2019-08-15
DNMT1is the dominating enzyme responsible for maintenance of the DNA methylation pattern and the primary enzyme responsible for copying methylation patterns following DNA replication (Moore et al., 2013). DNMT1 maintains the mitotic inheritance of the original methylation pattern in a cell lineage d
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Cytochrome P CYP enzymes plays an essential role in
2019-08-15
Cytochrome P450 (CYP-450) enzymes plays an essential role in pharmacology of drugs and toxicology of xenobiotics. Inhibition of these enzymes may lead to increase plasma levels of a concomitantly administered drug (Lee et al., 2013). It may prolong or reduce the pharmacological effects and increase
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br Materials and methods br Results br
2019-08-15
Materials and methods Results Discussion CDK and their regulatory cyclins form a family of heterodimeric kinases that are particularly important for regulation of Calcium Colorimetric Assay Kit progression and transcription in tumor cells. These kinases therefore constitute biomarkers of p
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br Conclusion br Introduction The morphological
2019-08-15
Conclusion Introduction The morphological variability of aquatic plants is well documented, and in some cases has seriously constrained taxonomic resolution (Sculthorpe, 1967, Santamaría, 2002). Many of these variations are caused by the extensive phenotypic plasticity of aquatic plants, but t
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br Particle swarm optimization for NLBP br Computational
2019-08-15
Particle swarm optimization for NLBP Computational tests Conclusions Acknowledgements This work was supported by the State Key Development Program for Basic Research of China (No. 2009CB421104) and the National Natural Science Foundation of China (Nos. 50809004 & 41071323). Main Text
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br Conclusion In conclusion DNA methylation is a major epige
2019-08-15
Conclusion In conclusion, DNA methylation is a major epigenetic mark, which regulates temporal and spatial expression of the testicular genes required for normal spermatogenesis process. There are two types of methylation, maintenance and de novo methylation, which are catalysed by DNMT1, DNMT3A
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Introduction Rotavirus RV a member
2019-08-15
Introduction Rotavirus (RV), a member of Reoviridae family, is a non-enveloped virus which has a double-stranded RNA genome of 11 segments surrounded by three concentric protein layers. It has been reported to cause estimated 25% of moderate-to-severe illnesses (Kotloff et al., 2013) and 30% of tot
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br Results br Discussion Adult hand foot and
2019-08-15
Results Discussion Adult hand, foot and mouth disease gets no particular research interest because it has been seen as a sporadic mild viral infection that spontaneously resolved in a few days. However, evidence showed that adults may act as latent enterovirus reservoirs. A serum epidemiologic
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br Conclusion In this study we
2019-08-15
Conclusion In this study, we have shown the construction, expression and purification of CPG2 fused to the HIV-1 TAT peptide (TAT–CPG2). We have demonstrated for the first time that TAT-CPG2 in both native and denatured forms could be efficiently transduced into the HepG2 cells. Also, we have pro
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More recent studies have correlated sPLA V with
2019-08-14
More recent studies have correlated sPLA2-V with alternative macrophage activation (M2) in human and murine macrophages [149,150]. sPLA2-V expression was induced during both human and mouse interleukin-4–mediated activation of macrophages in vitro, and its absence impaired macrophage activation in v
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We also found downregulation of TRIM
2019-08-14
We also found downregulation of TRIM32 in the hearts of dilated and hypertrophic cardiomyopathy patients in addition to TAC and phenylephrine treated mice [51]. TRIM32 and Dysbindin are known to interact in skeletal muscle, and we could confirm this interaction in cardiomyocytes as well. In cardiomy
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br Acknowledgement AM and SK thank ICMR New Delhi
2019-08-14
Acknowledgement AM and SK thank ICMR, New Delhi, India for the financial assistance BIC/12(32)/2012. SK is the recipient of JRF from the project. RK and GJ thank Bristol-Myer Squibb (Grant # 34003085), USA for financial support. Introduction Proliferating Cell Nuclear Antigen (PCNA) is a high
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We hypothesize that both IGF dependent
2019-08-14
We hypothesize that both IGF-1-dependent kinase activation and locally synthesized neuroestrogens interactively regulate estrogen receptor activity in neuronal Sodium Danshensu in the absence of exogenously applied estradiol. The Neuro-2A cell line was chosen as the model system for these studies b
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