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br Bisphosphonate use and breast
2019-05-30
Bisphosphonate use and breast cancer risk BPs are commonly used in the management of postmenopausal osteoporosis. They consist of two phosphate groups, which give them a high affinity to bone. They attach to bone at exposed calcium hydroxyapatite binding sites, which are most accessible at sites
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ALW-II-41-27 br Drug resistant tuberculosis threatens to und
2019-05-30
Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat
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Major outcomes from MADIT II trial suggested
2019-05-29
Major outcomes from MADIT-II trial suggested that, once again, the risk of death in defibrillator group was significantly less than conventional-therapy group with hazard ratio of 0.69. In this trial, the major drawback was corrected. The medication use remained balanced between ICD patients, and co
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Bone marrow DCE MRI performed
2019-05-29
Bone marrow DCE-MRI performed at diagnosis and complete remission of the acute myeloid leukemia (AML) patients, those multi-parametric data from DCE-MRI correlated significantly with treatment outcome. Three distinct parameters: peak enhancement ratio (Peak) to indicate tissue blood perfusion; ampli
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br Discussion Primary lymphoma of bone is
2019-05-29
Discussion Primary lymphoma of bone is a rare disease, first described by Oberling in 1928 and he labeled it as reticulum cell sarcoma of bone because of the presence of characteristic reticulin fibers within the lesion [5]. This work was followed by Parker and Jackson and later by Ivin and Bosto
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Our results are consistent with previous findings in
2019-05-29
Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].
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For single shot techniques like the CBA a
2019-05-29
For single-shot techniques, like the CBA, a modified spiral mapping catheter has been introduced for the identification of PVPs prior to ablation and also for monitoring purposes during the ablation process [6]. The Achieve™ Mapping Catheter (AC) is an intra-cardiac electrophysiological diagnostic c
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El siguiente cap tulo Carlos Monsiv is
2019-05-29
El siguiente capítulo, “Carlos Monsiváis: el momento de reconstrucción”, se centra en varios ensayos de . Bajo la tutela de de Žižek, Ruisánchez se acerca al ensayo “Los días del temblor” Purmorphamine través de la escritura del trauma, una lectura que resulta particularmente reveladora y poco común
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br History of cholesterol and bile
2019-05-29
History of cholesterol and bile Torin 1 research Bile is a yellow, brownish, or olive-green liquid that is composed primarily of water, organic solutes (such as lipids), inorganic salts, and some proteins. In bile, cholesterol, phospholipids, and bile acids are three major lipids, and bile pigme
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Limitations of meta analyses are often based
2019-05-28
Limitations of meta-analyses are often based on the strength of the data available. Only 26% of the eligible studies were judged to be at low risk of overall bias in this analysis. Other studies may have been at low risk for bias but failed to report information necessary for this determination. All
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vegfr inhibitor Much previous work highlights the rapid incr
2019-05-28
Much previous work highlights the rapid increases in DAH in the past decade, but in , Katherine Floyd and colleagues report that, in the case of tuberculosis, growth in domestic financing has been equally impressive. Their findings are convincing, especially in view of the fact that their study migh
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Repurposing use of approved drugs for new indications
2019-05-28
Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o
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I-BET-762 Na defini o da Secretaria Nacional de Pol ticas de
2019-05-28
Na definição da Secretaria Nacional de Políticas de Promoção da Igualdade Racial, vinculada atualmente ao Ministério dos Direitos Humanos do governo federal, as ações afirmativas são políticas públicas que têm como objetivo I-BET-762 correção de desigualdades raciais acumuladas ao longo dos anos na
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Introduction Hepatosplenic T cell lymphoma
2019-05-28
Introduction Hepatosplenic T-cell lymphoma (HSTCL) is a rare subtype of peripheral T-cell lymphoma, which is derived from cytotoxic T-cells typically expressing γδ T-cell receptor (TCR). It usually occurs in young men and is characterized by B symptoms such as a fever, weight loss and night sweats,
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Therefore the current study was
2019-05-28
Therefore, the current study was designed to investigate the effect of LS on coagulopathy and organ dysfunction in rats with endotoxemia induced by LPS, and to explore possible pathophysiological mechanisms. Previous studies have demonstrated that thromboelastography (TEG) appears to be a reliable m
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