• GW788388 In summary we have established

  2019-05-23

  

  In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibrom

• A coordena o atestada de valores hoje considerados

  2019-05-23

  

  A coordenação atestada de valores hoje considerados universais em regulamentos, estatutos, editais e leis setoriais pelo mundo indica o esquema de convergência de motivos e razões, e figuras sociais e jurídicas, que remete a uma intensificação da comunicação entre as diversas partes do planeta, send

• Pyraclonil Un peculiar texto de Borges

  2019-05-23

  

  Un peculiar texto de Borges enumera, al interior de su relato, interesantes ejemplos de varias categorías pertenecientes al idioma propuesto por John Wil-kins —un sabio inglés del siglo — cuyo objetivo fue diseñar un lenguaje mucho más completo, abarcador e incluso preciso, en sus descripciones del

• Another mechanism is that J waves represent a repolarization

  2019-05-23

  

  Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r

• There are several shortcomings to this study

  2019-05-23

  

  There are several shortcomings to this study that need to be considered. The small size of this series is an obvious shortcoming. Due to the relative rarity of the disease, this problem is not unique to this series and authors of a recent meta-analysis noted the small sample size of other studies as

• We present a case report of

  2019-05-23

  

  We present a case report of a patient with chronic myeloid leukemia (CML) who developed bilateral renal artery stenosis during tyrosine kinase inhibitor (TKI) therapy. Only a few reports associate TKIs with acute renal failure, and renovascular hypertension has not been previously described. Reports

• br The Millennium Development Goals on health

  2019-05-23

  

  The Millennium Development Goals on health have expanded access to basic health interventions to millions of people in low-income and middle-income countries (LMICs). However, access alone will not be sufficient to meet the Sustainable Development Goals (SDGs) if health systems cannot provide high

• Flow cytometric immunophenotyping showed the circulating bla

  2019-05-22

  

  Flow cytometric immunophenotyping showed the circulating blasts expressed CD19, CD20, CD22, CD24 partial, HLA -DR, CD34, and TdT. There was variable expression of the myeloid markers CD15 and CD33. The blasts were negative for CD3, CD10, MPO, and all other T-cell, myeloid, and monocytic markers eval

• HRU resulting from SREs is

  2019-05-22

  

  HRU resulting from SREs is of increasing relevance in times of financial and economic restraint because it can help to determine the financial burden to hospital managers and payers. A separate analysis of the costs associated with SREs in this study found that the most costly SRE, spinal cord compr

• Cerrone et al reported that the mechanism of CPVT was

  2019-05-22

  

  Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje

• br Point of care diagnostic tests POCTs

  2019-05-22

  

  Point-of-care diagnostic tests (POCTs) can enable health-care workers to provide more rapid and effective care to people in low-resource settings. POCTs should ideally meet the WHO\'s ASSURED criteria—ie, being affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and

• El libro de William Crawford publicado en traducido

  2019-05-22

  

  El libro de William Crawford publicado en 1944, traducido en 1966, y las obras de Leopoldo Zea de 1949 y de 1965, aunque de muy distinto carácter y alcance, suscitaron primero un artículo de Oscar Kubitz en 1960, después un ensayo de Salomon Lipp en 1975, y, finalmente, otro artículo de frank Spindl

• br En relaci n con este ltimo tipo de poes

  2019-05-22

  

  En relación con este último tipo de poesía, la escéptica, Baldomero Sanín Cano publica el artículo emblemático de la crítica modernista “Núñez, poeta” en 1888 en La Sanción. En este sentido, el crítico colombiano, David Jiménez afirma que este artículo “contiene ya los planteamientos fundamentales

• purchase JSH-23 Chronic myelogenous leukemia blast crisis is

  2019-05-22

  

  Chronic myelogenous leukemia blast crisis is highly refractory to standard induction chemotherapy, with a response rate of less than 20–30% [12,13]. In patient\'s with Imatinib resistant disease Dastanib and Nilotinib can help achieve hematological response however neither drug has been reported to

• Major outcomes from MADIT II trial

  2019-05-22

  

  Major outcomes from MADIT-II trial suggested that, once again, the risk of death in defibrillator group was significantly less than conventional-therapy group with hazard ratio of 0.69. In this trial, the major drawback was corrected. The medication use remained balanced between ICD patients, and co

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